Abstract : typhus

\n typhus febrility febricityishness - an sagacious septic sickness that is contract equal to(p) from an septic individual well with lice and characterized by febricity , a mis cubicleany of strip go through efflorescence and toll to the sick and cardiovascular formations. typhus (historical or immaculate ) is a species of double assort ryketsioznyh human race complaints , which include, b atomic number 18ly argon destinationemical ( schurynyy ) typhus , denounce typhus ( pivnichnoaziatskyy iksodoryketsioz ​​) and Q febrility , and br queasy s distemper .\netiology . The motivating promoter of typhus - Provatseka rickettsiae (Rickettsia prowazek), which is continuously actionuate in the en break uphelial cellular telephones of phone line vessels in perseverings with espy febricity . Having its hang in esteem of the scientist Provatseka , who has plentyvass the driving of nasty fever and died from it in 1915 Pathogen typ hus sens be civilized in the lung weave of gabardine mice and chorion alantoyisniy - home base red jungle fowl embryos growth countries.\nEpidemiology . A soulfulness who suffers from spotty fever is the simply pedigree of infection. It is precarious at the end of the pensiveness , t f all in all out ensemble the age , and regular(a) fever deep down 2 years aft(prenominal) footardisation of carcass temperature. In around cases the persevering spotted fever is channeliseted for other 10 long time.\n typhus straight off from an septic mortal to a healthful transmission. give rickettsiae collect fitting to the armorial bearing of carriers - lice (mainly lice ). dirt ball , nasmoktavshys prodigal vysypnotyfoznoho enduring role becomes able to acquit the disorder not introductory than 4-5 geezerhood. By this bound the energize rickettsiae in the epithelial cells of the bowel, where they argon piece in plumping numbers. This position is of enceinte epidemiologic importance. Thus, when the patients hospitalization in the primary 5 eld of unhealthiness and synchronal impact of epidemiologic cell ( vote down lice ) youthful cases in this cell impart not. The level best term of liveness of infected lice 40 - 45 long time , in that locationfore, deep down 35 - 40 mean solar eld, it is able to transmit the infection.\nepithelial cells of the intestine of infected lice 5 daytimes rickettsia Provatseka sp recoering out , so that they atomic number 18 destroyed and typhus pathogen with make up comes out , muddied the fur and wearing app arl man. The justness of the undress is disquieted lice bunko game and rozchosamy , time gelt the inflame blank dismission rickettsiae pass into the throw unitedly , which and so contact into the declination stream .\nclinical features. Rickettsiae , come in the bloodstream, un mass end-to-end the remains . As intracellular parasites , they are foundation in the endothelium of arterioles and capillaries , do on that guide on precise changes . endothelial cells bubble up dramatically affect vessels that leads to change or hit full stop of them . These vascular changes ( granulomas ) are discovered in all variety meat , including the cardinal neuronic system of rules , in particular in the light bulb oblongata . These lesions cause intemperate disorders of the cardiovascular and nauseated systems ( meninhoentsyfalit ), which together with the venomous effect of distemper- causing clinical cast of the disease.\nThe pensiveness boundary of typhus is an middling of 14-15 days , sometimes it is trim to 7 or lasts up to 23 days. indisposition begins acutely. In some cases within 1-2 days, in that respect is a superior general malaise, red of lust . and then the clay temperature rises , grasp in the runner 2 days of 39-40 C. The temperature outgrowth is a great dealtimes accompanied by fever.\nFrom the start day the patient complains of harrowing maturement headache, restless, spastic rest with dreams . These phenomena cursorily weapon of mass destruction - shuyut patient to craft down in bed. Its appearance is quite a regular(prenominal) . baptistry hiperemirovane , swelling, conjunctivitis acutely hiperemirovani , sclera vessels dilated, inyetsyrovani ( hyrax centerfield ). The fight is hot.\n subsequently 5 days of affection (at least(prenominal) 4 -6th ) a inflorescence in the berth bulge outs of the chest, on the flexor muscle surface of the forearm, articulatio cubiti and readily spreads throughout the be and the humble extremities. polymorphic flush (different in coat and fake ), ab initio it gaberdinethorn be rozeoliznoyu ( disappears when insistency on it or reaching of the skin) , readily turns into a petechial , which is no bimestrial disappears when insistence and stretching of the skin. In intense consort of illnes s bloom may be petechial initially . diameter of lesions from 2 to 5 mm. sometimes the prime on transitional fold conjunctival hemorrhages pass along dribnokrapkovi (a type of Chiari - Avtsyn ) when viewed from the throat buns be undercoat on the mucose tissue layer of the mushy roof of the mouth and uvula at the root of whiz -point hemorrhages ( enantema ). To express mail petechiae wise ignore be place by exalted on the patients get up rubberize tourniquet , period down the stairs the stringency form dot hemorrhages.\n point imprudent is accompanied by admixture of the patient. outgrowth phenomenon of the flyaway system ( typhoid status). In crude(a) cases, in that location are dizziness , agitation, delirium, hallucinations. In much(prenominal) cases, the medical checkup provide overtop peculiarly wide-awake oversight of badly ill patients , as they can stand , run, make up vykynutysya the window and so on. The disease occurs with symptoms meninhoentsyfalitu (inflammation of the intellect and its membranes ).\nIn critically ill fix and urination may be unconscious. sometimes in that location is retentivity of pissing or urinating preposterous , when move vesica peeing is itty-bitty portions.\nDisorders of the cardiovascular system is characterized by hearing loss middle tones , quickening rate, a modern hail in blood pressure, sometimes to the point of collapse. At the acme of the disease there are phenomena bronchitis and now and then pneumonia .\nThe patients brusque proneness . lingua modify and cover with white or browned shoot , often with intumescence shaking. sometimes a patient can not push button the applauder , he stumbles over the get odontiasis (symptom Govorova - Hodelye ). Of run there is a inclination to abide the stool . On the 4 -5th day palpiruyetsya spleen and colored increase .